Phenyl salicylate

“Salol” redirects here. Salol may also refer to Salol, Minnesota.

Phenyl salicylate[1]

Names

IUPAC name
Phenyl 2-hydroxybenzoate

Other names
Salol

Identifiers

CAS Number

118-55-8 Y

3D model (Jmol)
Interactive image

ChEBI
CHEBI:34918 N

ChEMBL
ChEMBL1339216 N

ChemSpider
8058 N

ECHA InfoCard
100.003.873

EC Number
204-259-2

KEGG
C14163 N

MeSH
C026041

PubChem
8361

InChI

InChI=1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H N
Key: ZQBAKBUEJOMQEX-UHFFFAOYSA-N N

InChI=1/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
Key: ZQBAKBUEJOMQEX-UHFFFAOYAI

SMILES

O=C(Oc2ccccc2)c1c(O)cccc1

Properties

Chemical formula

C13H10O3

Molar mass
214.22 g/mol

Appearance
White solid

Density
1.25 g/cm3

Melting point
41.5 °C (106.7 °F; 314.6 K)

Boiling point
173 °C (343 °F; 446 K) at 12 mmHg

Solubility in water

1 g/6670 mL

Magnetic susceptibility (χ)

-123.2·10−6 cm3/mol

Refractive index (nD)

1.615[2]

Pharmacology

ATC code

G04BX12 (WHO)

Hazards

Flash point
137.3[2] °C (279.1 °F; 410.4 K)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is YN ?)

Infobox references

Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It can be created by heating salicylic acid with phenol. Once used in sunscreens, phenyl salicylate is now used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes.[1] It is also used frequently in school laboratory demonstrations on how cooling rates affect crystal size in igneous rocks.
Salol reaction[edit]
In the salol reaction, phenyl salicylate reacts with o-toluidine in 1,2,4-trichlorobenzene at elevated temperatures to the corresponding amide o-Salicylotoluide.[3] Salicylamides are one type of drug.
Medical[edit]
It has been used as an antiseptic[4] based on the antibacterial activity upon hydrolysis in the small intestine.[citation needed]
It acts as a mild analgesic.[5]
References[edit]

^ a b Merck Index, 11th Edition, 7282.
^ a b ChemBK Chemical Database http://www.chembk.com/en/chem/Phenyl%20salicylate
^ Allen, C. F. H.; VanAllan, J. (1946). “SALICYL-o-TOLUIDE” (PDF). Org. Synth. 26: 92. ; Coll. Vol., 3, p. 765 
섹스